Anti- Amanitin monoclonal antibody
抗Amanitin鼠單克隆抗體
編號(hào): YKMP18070
貨期:現(xiàn)貨
規(guī)格:25ug/100ug/1mg
Background
α-Amanitin is the principal toxin of several deadly poisonous mushrooms, exerting its toxic function by
inhibiting RNA-polymerase II. α-Amanitin decreases TAF15 mRNA and TAF15 protein levels in MKN45
cells, and inhibits the RNAPII activity towards TAF15 mRNA. α-Amanitin dramatically decreases the expression of gap junctional genes (Gja1, Gja4 and Gjc1) and FSHr and LHr in cumulus cells.
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